Simply the Fundamentals For Focus, Power, and Pump

When new manufacturers hit the scene, there’s sometimes an enormous push to return out of the gate by going excessive. New children want to distinguish themselves from the gang, in spite of everything, or they get misplaced in it. Each model wants an edge – a singular promoting level that makes a splash. Sometimes, this implies loaded formulation with excessive ingredient dosages and wild bottle artwork.

One new model has determined to go in a totally different course.

Primary Dietary supplements Primary Pre brings simply what’s wanted for focus, vitality, and pumps, with 200mg caffeine and 3g citrulline per scoop — and it’s inexpensive with no tingles!

Primary Dietary supplements is strictly what it appears like – a model devoted to getting again to the fundamentals. Launched by Marc Curcio and Laura Valley in Episode #156 of the PricePlow Podcast, they’re solely a pair months outdated, however have hit the market like a breath of recent air.

At this time, we’ll go over their Primary PRE Pre-Exercise, which gives the fundamentals you want for focus, vitality, and pump. And no tingles!

Simplicity Results in Dependable Outcomes

In the event you take a look at many pre-workouts lately, the ingredient record is a mile lengthy, crammed with proprietary commerce names and unpronounceable components. Many of those components have legitimate makes use of, however they add vital value (and processing in your liver) to attain a marginal enhance if you’re already 80% of the way in which there with 4-5 staple components.

Staple components – confirmed compounds like citrulline, creatine, and caffeine – might not be distinctive at this level, however that’s as a result of they work. That’s why practically each lively vitamin firm makes use of them. Primary has taken it a step additional by including arginine to assist increase the citrulline and referred to as it a day. No magnifying glass required to learn the label.

We’re going to dive into how Primary PRE works, however first, let’s test PricePlow for good Primary offers and watch our video assessment of the brand new product:

Primary PRE Elements

Every 1 scoop (8g) serving incorporates the next components:

• L-Citrulline – 3000mg

  

  L-citrulline is a non-essential amino acid identified for its potential to considerably increase nitric oxide manufacturing, enhancing blood movement, oxygen, and nutrient supply within the physique.^[1,2] Discovered naturally in meals like watermelon, L-citrulline is a key ingredient in pre-workouts attributable to its performance-enhancing properties, notably its potential to enhance endurance and amplify muscle pumps.

  The effectiveness of L-citrulline lies in its position within the physique’s ureagenesis cycle, the place it helps take away ammonia, a byproduct that may impair vitality manufacturing.^[1] L-citrulline is transformed into L-arginine within the kidneys, resulting in nitric oxide (NO) manufacturing,^[3] inflicting vasodilation (growth) of blood vessels.^[4] This vasodilation improves blood circulation throughout train, enhancing oxygen uptake, lowering perceived exertion, reducing blood strain, and reducing muscle soreness.^[1,2,5-10]

  The three grams of citrulline right here exceeds the two.4-gram clinically validated dose seen in analysis,^[2] offering roughly the equal of 6 grams of citrulline malate, which has been proven to advertise cardio vitality manufacturing.^[11]

  Apparently, L-citrulline can also be an arginase inhibitor, stopping the breakdown of arginine.^[12-14] Extra on this later.

• Creatine Monohydrate – 1500mg

  Creatine, a naturally occurring substance discovered primarily in meat, is among the most researched and efficient sports activities dietary supplements. It’s been proven to considerably enhance energy output, hydration, dash velocity, lean muscle mass, and total well-being whereas lowering fatigue.^[15-20] Some research additionally recommend slight boosts in testosterone, bone mineral density, and cognitive perform, notably in individuals who don’t devour meat.

  

  The primary taste to launch in Primary Pre: Ice Pop!

  Creatine works by donating a phosphate group to ADP, which helps regenerate ATP^[21-24]; this course of is essential for mobile vitality. This enables athletes to carry out higher for longer and construct extra lean mass than they’d with out creatine supplementation.

  Analysis on creatine spans a number of a long time, with quite a few meta-analyses confirming its advantages. It persistently enhances muscle development andpreserves lean mass.^[15-19] Moreover, creatine improves energy output, as demonstrated by elevated one-rep maxes and higher efficiency in high-intensity, short-duration workout routines.^[20] Whereas it’s best for actions like weightlifting and sprinting, creatine additionally presents psychological advantages, enhancing temper and cognitive perform,^[25-27] particularly in people with low meat consumption.

  How a lot creatine do you want? It relies upon…

  In terms of dosing creatine, how a lot you want actually is dependent upon your weight loss plan, physique dimension, and saturation ranges. As an example, males excrete about two grams of creatine per day^[28] (this varies with muscle mass and dimension), utilizing about 1.6-1.7% of creatine shops every day.^[29,30] Girls lose barely much less.^[28]

  So do you want 3-5 grams of creatine per day, as most declare? Not essentially, particularly should you eat meat or are a girl or smaller particular person.

• L-Arginine Alpha Ketoglutarate 2:1 – 400mg

  Whereas citrulline converts first into arginine earlier than elevating NO ranges, it’s really more practical than arginine in isolation. It is because citrulline is extra proof against breakdown within the abdomen and liver than arginine, permitting it to achieve the kidneys and bloodstream earlier than being transformed into arginine. Consequently, normal apply has been to complement citrulline as a substitute of arginine.

  

  The Arginine Citrulline Cycle with a breakout displaying the arginine-to-nitric oxide response. Picture courtesy Wikimedia with added biochemistry sources.^[31,32]

  Nonetheless, analysis means that the mixture of the 2 components is much more efficient than citrulline alone. Citrulline inhibits the enzyme arginase, which degrades orally administered arginine, thereby enhancing the results of arginine.^[12]

  A 2017 examine carried out in Japan examined three teams of volunteers: one taking citrulline, one taking arginine, and one taking a mix of each.^[12] The outcomes confirmed that the citrulline-arginine mixture considerably outperformed the opposite teams, reaching larger plasma arginine ranges and higher nitric oxide manufacturing, which contributes to improved blood movement and circulation.^[12] The examine concluded that the mixture of citrulline and arginine led to virtually double the quantity of plasma arginine in comparison with these not supplementing, displaying clear advantages for growing nitric oxide ranges.^[12]

  

  In fall of 2024, Mike and Ben flew to Buffalo, NY to Nutrablend Meals, producer for the brand new upstart model, Primary Dietary supplements. They interview Marc Curcio and Laura Valley for Episode #156, discussing how they’re simplifying the complement trade with high-quality, important merchandise which are each inexpensive and clear.

  These findings have been additional supported by a 2019 examine involving faculty athletes, which demonstrated improved efficiency when citrulline and arginine have been mixed.^[13] The athletes confirmed a 5% enhance in energy output on a stationary bike check, with decreased muscle soreness and improved ease of pedaling, indicating that the citrulline-arginine mixture enhances nitric oxide ranges and gives tangible advantages in athletic efficiency and restoration.^[13]

  These outcomes have additionally been validated in animal fashions, the place comparable results on blood movement and arginine ranges have been noticed,^[14] reinforcing the efficacy of this mixture in enhancing each cardiovascular and athletic efficiency.

  Whereas 400 milligrams of arginine typically received’t promote vital clinically-backed nitric oxide positive aspects by itself, it may well synergize with citrulline to supply a bit extra, retaining the pre-workout’s prices down.

• Caffeine Anhydrous (200mg)

  Caffeine is among the most researched dietary supplements, persistently proven to boost each bodily and psychological efficiency. It really works by blocking adenosine receptors, lowering neural exercise and boosting vitality ranges.^[33,34]

  

  Moreover, caffeine inhibits the enzyme phosphodiesterase, which will increase ranges of cAMP, resulting in better ATP manufacturing and vitality.^[33,34] Analysis additionally signifies that caffeine reduces ache notion and aids in fats loss.^[33,34]

  200 milligrams of caffeine is a good and modest quantity—it was once the usual till the usual modified. However as you guessed, Primary Dietary supplements is getting again to the fundamentals—this can be a product that may be loved by practically anybody. You may all the time take extra, in spite of everything.

  There’s additionally analysis supporting this dose—a average 3 mg/kg dose (200 mg for a 150-pound individual) confirmed enhancements in response time, efficiency, and fewer errors when taking part in tennis.^[35] 200 mg has additionally been proven to cut back response instances,^[36] which shouldn’t shock anybody who’s used it!

• Huperzia Serrata Extract (1% Huperzine A) – 2mg

  Huperzine A is a compound that prolongs the motion of acetylcholine, the neurotransmitter accountable for studying and cognition, by inhibiting the enzyme that breaks it down.^[37]

  Even by itself, huperzine A can increase cognitive perform by growing acetylcholine ranges.^[38] Moreover, it protects neuronal mitochondria from oxidative stress,^[39] additional enhancing its nootropic results and making it a worthwhile ingredient for supporting mind well being and psychological efficiency.

  

  This dose results in 20mcg of Huperzine A, which is a snug dose to kick it up a small notch, however not final too lengthy.

All Primary PRE flavors

Take a look at our up-to-date record of Primary PRE flavors beneath:

So Peculiar That It’s Daring

There are actually customers who like to experiment with novel components — to remain on the chopping fringe of efficiency supplementation. In your common Joe, although, he needs solely what has been confirmed to work.

Primary Supps’ formulation are so regular that all the model’s ethos may very well be described as daring, as paradoxical as that sounds. When the gang is attempting to dazzle with confetti and fireworks, the best act of revolt is to take pleasure within the fundamentals.

Want extra? You may head again to our important introductory Primary Dietary supplements article, hearken to Episode #156 of the PricePlow Podcast, and see our article on Primary Whey — the Boston Cream Donut taste is unbeatable!